CategoryKnowledge
MeasureAccuracy
Tasks504 molecular-property questions
DifficultyMedicinal chemistry reasoning
Selects compounds with the highest or lowest measured ADME-related property from molecular structures and reference values.
Medicinal chemistry ranking
2 models with a published Medicinal chemistry value, ordered by that value, highest first. Models the source has not scored on this benchmark are not listed — they are unmeasured, not last.
Models ranked by their published Anthropic medicinal-chemistry evaluation value| Rank | Model | Provider | Accuracy |
|---|
| 1 |  Claude Sonnet 5.5 | Anthropic | 65.3 |
| 2 | Claude Opus 5.5 | Anthropic | 63.5 |
Evidence key: Observed
Rows are ordered by the value Claude Opus 5.5 System Card published, highest first. The source does not state whether a higher value is the better result, so this page does not either: for a benchmark that measures a rate of failure, read the table from the bottom.
About Medicinal chemistry
What the benchmark measures and how its value is published, from the source’s own record.
What is Medicinal chemistry?
Medicinal chemistry (Anthropic medicinal-chemistry evaluation) is a knowledge benchmark published by Claude Opus 5.5 System Card. Selects compounds with the highest or lowest measured ADME-related property from molecular structures and reference values. Its evaluation set is described by the source as 504 molecular-property questions. The source rates its difficulty as medicinal chemistry reasoning.
How is Medicinal chemistry scored?
Each model's result is published by Claude Opus 5.5 System Card as accuracy. ModelScale prints that value to 1 decimal place, exactly as published, and never converts or rescales it. This page ranks the 2 models that carry a published value, highest value first; a model the source never scored is left out rather than ranked at zero. The source does not state whether a higher value is the better result, so neither does this page.
ModelScale